منابع مشابه
Fetal valproate syndrome.
There is an increased incidence of major and minor congenital abnormalities in infants born to epileptic mothers (6 to 7% compared with 2 to 3% in the general population).' Factors which may contribute to this include the occurrence of seizures leading to periods of hypoxia during pregnancy, an inherited predisposition to malformations owing to intrinsic maternal factors, and the teratogenic ef...
متن کاملPrenatal sonographic diagnosis of fetal valproate syndrome: a case report
BACKGROUND Prenatal exposure of mother to valproate (VPA) causes teratogenic effects in the fetus, namely fetal valproate syndrome (FVS). We report a case of fetal valproate syndrome rarely diagnosed by prenatal sonographic examination. CASE PRESENTATION Our patient was a female infant who was born to a 27-year-old nulliparous Japanese woman with epilepsy. The mother was diagnosed with infant...
متن کاملFetal Valproate Syndrome with Limb Defects: An Indian Case Report
Epilepsy is a common disorder and exposure to antiepileptic drugs during pregnancy increases the risk of teratogenicity. Older AEDs such as valproate and phenobarbital are associated with a higher risk of major malformations in the fetus than newer AEDs like lamotrigine and levetiracetam. Exposure to valproic acid during first trimester can result in fetal valproate syndrome (FVS), comprising t...
متن کاملFetal valproate syndrome: is there a recognisable phenotype?
Four infants who were exposed to sodium valproate or valproic acid during pregnancy are described. Common facial features in the three surviving infants include epicanthic folds, a flat nasal bridge, a broad nasal base, anteverted nostrils, a shallow philtrum, and a thin upper lip with a thick lower lip. Ridging of the metopic suture, congenital heart defect, postaxial polydactyly, and hypospad...
متن کاملFetal Alcohol Syndrome
Background: About 40 thousand newborns are delivered annually with fetal alcohol syndrome (FAS). It induces serious CNS complications. Methods: In a review of, the word “fetal alcohol syndrome” was searched in PubMed and Google Scholar and the retrieved articles were summarized. Results: Many studies showed that alcohol can cause more defects in fetus than heroin, cocaine and marijuana. The pos...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1993
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-7-11-6